Product Knowledge

Onyxide 500, Lexgard & Myacide Bronopol Alternative — India Manufacturing

Onyxide 500 (Lonza), Lexgard Bronopol, and the Myacide range are well-known branded Bronopol products used globally. This guide explains what these brands have in common with genuine Bronopol, why buyers evaluate India-manufactured alternatives, and how to validate equivalence before switching suppliers.

Published 2026-01-20Updated 2026-07-27By Vasudev Chemo Pharma Technical TeamReviewed by Vasudev Chemo Pharma Export & Compliance Team, International Trade, Chemical Exports

What Do Onyxide 500, Lexgard, and Myacide Have in Common?

Onyxide 500, Lexgard Bronopol, and the Myacide range (AS Plus, BT, Pharma BP) are branded trade names for the same active substance — Bronopol, CAS 52-51-7 — supplied at high purity as a crystalline solid or in liquid solution form by different manufacturers.

These brands built market recognition through established supply relationships with cosmetic, pharmaceutical, and industrial manufacturers, and many formulation specifications and legacy technical documents still reference brand names by default, even when the underlying requirement is simply "Bronopol, CAS 52-51-7" meeting a defined purity specification.

Why Do Buyers Evaluate an India-Manufactured Alternative?

Buyers evaluate alternatives to reduce landed cost, shorten lead times for Asia/Middle East/Africa markets, diversify supply chains, and access more direct manufacturer technical support — standard risk-management practice, not a reflection on the original brand's quality.

India has an established base of Bronopol manufacturers serving both domestic and export markets, offering buyers in Asia, the Middle East, and Africa shorter transit times than European- or American-origin shipments, alongside potential cost advantages once freight and duty structures are accounted for.

How Do I Validate Equivalence Before Switching Suppliers?

Compare specification sheets (assay, melting point, appearance), request and quality-check a sample, run a small-batch formulation trial with preservative efficacy testing against a control, and complete accelerated storage stability trials before full-scale substitution.

First, compare specification sheets side by side — assay/purity, melting point, appearance, and moisture content should align closely with your current specification or the reference brand's published technical data. Second, request a sample and run it through your standard incoming raw material quality control checks, including assay verification. Third, run a small-batch formulation trial substituting the alternative product at the same nominal dosage, and put the trial batch through your standard preservative efficacy test alongside a control batch made with your current material. Fourth, run accelerated and real-time storage stability trials on the substituted batch to confirm no unexpected colour, odour, or performance drift over the product's intended shelf life.

Supplier qualification checklist for switching Bronopol sources
Step	Action	Pass criterion
1. Specification comparison	Compare assay, melting point, appearance, moisture content	Within specification tolerance of current material
2. Sample QC	Independent assay verification on received sample	Matches COA-stated assay range
3. Formulation trial	Small-batch substitution at same nominal dosage	Passes preservative efficacy test (ASTM E640 / ISO 11930)
4. Stability trial	Accelerated and real-time storage testing	No unexpected colour, odour, or performance drift

Frequently asked questions

Is Vasudev Chemo Pharma's Bronopol the same chemical as Onyxide 500?+

Yes, both are the same active substance — Bronopol, CAS 52-51-7 — supplied at high purity. Confirm equivalence on assay, melting point, and other specification parameters before substituting.

Why would I switch from an established Bronopol brand to an Indian supplier?+

Common reasons include reduced landed cost, shorter transit times for Asia, Middle East, or Africa buyers, supply chain diversification, and more direct manufacturer technical support — standard supply-chain risk management, not a reflection on the original brand.

What should I check before substituting an alternative Bronopol supplier?+

Compare specification sheets (assay, melting point, appearance), request and test a sample, run a small-batch formulation trial with preservative efficacy testing, and complete accelerated storage stability testing before full-scale substitution.

Can Vasudev Chemo Pharma support a formal supplier qualification process?+

Yes. We provide samples, Certificates of Analysis, Safety Data Sheets, and technical support to help buyers complete side-by-side qualification trials against their current specified brand before switching.