Bronopol (CAS 52-51-7)
Speciality Chemicals

Bronopol

Formula: C₃H₆BrNO₄CAS No.: 52-51-7Mol. Wt: 199.99 g/mol
Product NameBronopol
SKUVCP-IND-0008
CategorySpeciality Chemicals
SubcategoryBiocides & Preservatives
OriginIndia
ManufacturerVasudev Chemo Pharma
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Export: 1 MT minimum order  ·  Domestic: 25 kg minimum order

Quick answer

Bronopol (2-Bromo-2-nitropropane-1,3-diol, CAS 52-51-7) is a broad-spectrum antimicrobial preservative supplied as a white to pale-yellow crystalline powder. It is fast-acting against gram-negative bacteria including Pseudomonas aeruginosa, and is used in cosmetics, water treatment, metalworking fluids, and paper mill systems at typical use levels of 0.02% to 0.1%.

About Bronopol

Bronopol (2-Bromo-2-nitropropane-1,3-diol) is a fast-acting, broad-spectrum antimicrobial preservative widely used to control bacteria in personal care formulations, industrial water systems, and metalworking fluids. It offers excellent activity against Gram-negative bacteria and is compatible with a wide range of surfactants and formulation ingredients. Manufactured by Vasudev Chemo Pharma at our ISO 9001:2015 certified facility in Gujarat, India.

Technical Specifications

ParameterValue
Assay≥ 99%
AppearanceWhite to pale yellow crystalline powder
Melting Point130 – 133°C
Moisture Content≤ 0.5%
Solubility in WaterReadily soluble
pH (1% aqueous solution)5.0 – 6.0

Appearance

White to pale yellow crystalline powder

Molecular Weight

199.99 g/mol

HSN Code

29049090

Applications & Industries

Applications

Preservative for cosmetics and personal care productsIndustrial water treatment biocideMetalworking and cutting fluid preservationPreservative for household cleaning productsOilfield biocide for drilling and completion fluidsAdhesive and coating preservation

Target Industries

Personal Care & CosmeticsWater TreatmentMetalworking & LubricantsOil & GasHome CareAdhesives & Coatings

Safety & Compliance

GHS Classification

Safety Class: Corrosive/Irritant

Signal Word: Danger

GHS05GHS07GHS09

Hazard Statements

  • ⚠H302 – Harmful if swallowed
  • ⚠H314 – Causes severe skin burns and eye damage
  • ⚠H317 – May cause an allergic skin reaction
  • ⚠H400 – Very toxic to aquatic life

Packaging Options & Available Grades

Available Grades

  • Technical Grade
  • Cosmetic Grade
  • Industrial Grade

Packaging

  • 25 kg fibre drums
  • 25 kg HDPE bags with liner
  • Custom packaging on request

Minimum Order Quantity

25 kg

Certifications & Quality Assurance

ISO 9001:2015

Documents & Downloads

Content to add

Downloadable documents — Safety Data Sheet (SDS/MSDS), Certificate of Analysis (COA), Technical Data Sheet (TDS), Product Specification Sheet. Each with file type, access level (public / on-request).

Shipping & Export Information

Content to add

Shipping & export details — Export-ready packaging, nearest ports (Kandla, Mundra, Hazira), shipping lead time, Incoterms offered (FOB, CIF, CFR), countries exported to, customs documentation support, HS code for this product.

Frequently Asked Questions

What is Bronopol and what is it used for?+
Bronopol (2-Bromo-2-nitropropane-1,3-diol, CAS 52-51-7) is a broad-spectrum antimicrobial preservative supplied as a white to pale-yellow crystalline powder. It is used in cosmetics and personal care products, pharmaceutical formulations, industrial water treatment, metalworking fluids, paper mill systems, and oilfield chemicals to control bacterial contamination.
What is the CAS number and molecular formula of Bronopol?+
Bronopol has CAS number 52-51-7, molecular formula C3H6BrNO4, and molecular weight 199.99 g/mol. It is also known by the EC/EINECS number 200-143-0 and UN Number 3241 for transport. Its INN (International Nonproprietary Name) is simply Bronopol.
Is 2-Bromo-2-nitropropane-1,3-diol the same as Bronopol?+
Yes. Bronopol, 2-Bromo-2-nitropropane-1,3-diol, 2-Bromo-2-nitro-1,3-propanediol, and 1,3-Propanediol 2-bromo-2-nitro- all refer to the same active substance under CAS 52-51-7. Trade names including Bronocot, Bronosol, Onyxide 500, and Lexgard Bronopol also reference this identical compound.
How does Bronopol work as an antimicrobial preservative?+
Bronopol's antimicrobial action is based on cross-linking sulfhydryl (thiol) groups in dehydrogenase enzymes on microbial cell surfaces, forming disulfide bridges that block cellular respiration and metabolism. This mechanism is highly effective against gram-negative bacteria, particularly Pseudomonas species, and does not primarily rely on formaldehyde release.
Is Bronopol a formaldehyde-releasing preservative?+
Bronopol's primary antimicrobial activity comes from its electron-deficient bromine atom, not formaldehyde release. However, under alkaline conditions and elevated temperature, Bronopol can decompose and liberate low levels of formaldehyde and nitrite as secondary breakdown products, which is why it should not be combined with secondary amines in formulations.
What is the recommended use level of Bronopol in cosmetics?+
Typical use levels for Bronopol in cosmetic and personal care formulations range from 0.02% to 0.1% (200-1,000 ppm), with most formulations dosed below the regulatory maximum limit. Confirm the current permitted concentration limit in your target market before finalising a cosmetic formulation, as regulations vary by jurisdiction.
What pH range is Bronopol most stable in?+
Bronopol is most stable in aqueous solution at acidic to neutral pH (around pH 5.0-5.5 for a 1% solution). Stability decreases significantly at alkaline pH and elevated temperature, where decomposition accelerates and formaldehyde and nitrite release increases. Citric acid is commonly used to stabilise Bronopol solutions by lowering pH.
Is Bronopol safe for use in leave-on cosmetic products?+
Bronopol's use in cosmetics has declined since the late 1980s due to nitrosamine formation risk when it decomposes in the presence of secondary amines or amides. Regulatory bodies in several markets, including Canada, have placed restrictions on Bronopol in certain cosmetic product categories — always confirm current permitted use and concentration limits for your target market.
What industries use Bronopol besides cosmetics?+
Beyond personal care, Bronopol is widely used in industrial water treatment (cooling towers, air washer systems), metalworking and cutting fluids, paper mill and pulp processing, oilfield systems including drilling and production fluids, paints and adhesives, and household cleaning products, owing to its broad-spectrum activity and stability in aqueous systems.
Is Bronopol classified as hazardous?+
Bronopol is classified with the GHS signal word Danger, including hazard statements for acute oral and dermal toxicity (H302, H312), skin and eye irritation/damage (H315, H318), and respiratory irritation (H335). Aquatic toxicity classification (e.g. H410 vs H411) varies by regulatory jurisdiction and SDS version, so always refer to the jurisdiction- and batch-specific SDS supplied with your shipment rather than treating any single aquatic hazard code as universal. Standard PPE — gloves, eye protection, and adequate ventilation — is required when handling the concentrate.
What packaging and grades does Vasudev Chemo Pharma supply Bronopol in?+
Vasudev Chemo Pharma supplies Bronopol in Technical, Cosmetic, and Industrial grades, packaged in 25 kg fibre drums and 25 kg HDPE bags with liner, with custom packaging available on request. Every shipment includes a batch-specific Certificate of Analysis (COA) and Safety Data Sheet (SDS), with Technical Data Sheets available on request.
How is Bronopol different from BIT (Benzisothiazolinone)?+
Bronopol (CAS 52-51-7) and BIT (CAS 2634-33-5) are chemically distinct preservatives. Bronopol is a nitro-bromo compound that is fast-acting against gram-negative bacteria, particularly Pseudomonas; BIT is an isothiazolinone with broader gram-positive, fungal, and yeast coverage plus better long-term thermal and pH stability. The two are frequently used together in blended preservative systems.

Speciality Chemicals — Bronopol (2-Bromo-2-nitropropane-1,3-diol)

Applications, Supply & Global Distribution

Bronopol (2-Bromo-2-nitropropane-1,3-diol, CAS 52-51-7) is a broad-spectrum antimicrobial preservative manufactured by Vasudev Chemo Pharma, supplied as a white to pale-yellow crystalline powder. It is fast-acting against gram-negative bacteria, particularly Pseudomonas species, and is used across cosmetics and personal care, pharmaceutical preservation, industrial water treatment, metalworking fluids, paper mills, and oilfield systems. A direct alternative to Onyxide 500, Lexgard Bronopol, and Myacide grades.

Industry Applications

Cosmetics, Personal Care & Pharmaceutical Preservation

Bronopol preservation for shampoos, lotions, cosmetics, and pharmaceutical formulations, with fast-acting activity against gram-negative bacteria including Pseudomonas.

Water Treatment, Paper Mills & Oilfield Systems

Bronopol biocide for cooling water systems, paper mill slime control, and oilfield drilling and production fluid preservation.

Global Supply of Bronopol (CAS 52-51-7) Preservative

Bulk Supply & Packaging Options

Available in 210L drums, 1 MT IBC tanks, ISO tanks, flexitanks, and bulk containers. Factory direct pricing from Gujarat, India.

Contract Manufacturing & White Label Supply

Private label, white label, and contract manufacturing services for H2S scavenger chemicals. OEM supply from ISO 9001:2015 certified facility.

Chemical Trading & Procurement

B2B supply, chemical trading, procurement services, and competitive pricing. Available on IndiaMart, Alibaba, and TradeWheel.

Related Products & Resources

BIT 20% (Benzisothiazolinone)Broader-spectrum isothiazolinone preservative, often paired with BronopolSodium DimethyldithiocarbamateBiocide and heavy-metal precipitant for water treatmentPersonal Care & CosmeticsPreservatives and surfactants for cosmetics and personal care formulationsWater Treatment IndustryChemical solutions for water treatmentMetalworking Fluids IndustryBiocides and preservatives for metalworking fluidsPaper & Pulp IndustryBiocides for paper mill applicationsBronopol Dosage GuideRecommended use levels and preservative efficacy testingBronopol Price & Supplier GuidePricing factors, MOQ, and evaluating a reliable supplierBronopol vs BIT (Benzisothiazolinone)Compare the two preservatives and when to combine themBronopol Safety, Handling & StorageGHS hazards, PPE, storage conditions, and spill responseBronopol Uses in Cosmetics & Personal CareShampoos, lotions, and personal care regulatory limitsBronopol Nitrosamine Formation RiskMechanism, secondary amine incompatibility, and mitigationBronopol for Water Treatment & Cooling TowersCooling water and air washer system preservationBronopol for Metalworking Fluids & Cutting OilsDosage and compatibility in cutting oil concentratesBronopol vs Formaldehyde DonorsMechanism comparison and regulatory positioningBronopol for Paper Mill & Pulp ProcessingSlime control applications in paper manufacturingBronopol for Oilfield Drilling FluidsSRB control in drilling and production systemsOnyxide 500 / Lexgard / Myacide Bronopol AlternativeBrand equivalence and supplier qualification guidanceBronopol Technical Data (CAS 52-51-7)Complete chemical identity and physical property referenceBronopol Mechanism of Action & Pseudomonas ControlAntimicrobial mechanism deep-diveBronopol Pharmacopoeia Grades (IP/BP/Ph.Eur.)Grade differences and pharmaceutical useBronopol Stability: pH & TemperatureDecomposition chemistry and stabilisation methodsBronopol Allergy, Toxicity & Environmental ImpactDermatitis, aquatic toxicity, and regulatory statusBronopol for Household Cleaning ProductsDetergents and household cleaner preservationBronopol Compatibility with SurfactantsFormulation compatibility guideBronopol vs Parabens Preservative ComparisonComparing Bronopol with paraben-based preservativesAll ProductsBrowse our full chemical product catalogAbout UsISO 9001:2015 certified manufacturer in Gujarat, IndiaRequest a QuoteGet pricing and samples within 24 hours

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